Skin and hair health

2025-09-27

The Difference Between Mesogel and Under-eye Filler: Which is the Better Choice?

The beauty and freshness of the under-eye area play a very important role in the youth and freshness of the face. Darkness, hollows, or fine wrinkles under the eyes can cause fatigue or increase the appearance of age, even in young people. Today, there are two popular methods to improve these problems: under-eye filler injections or mesogel (skin boosters). But what is the difference between the two, and which is more suitable for you? In this article, we will scientifically, practically, and simply examine these differences and answer the most common questions of users.

What is under-eye filler injection in Iran, and what does it do?

Under-eye fillers are usually made of cross-linked hyaluronic acid (HA); that is, they have a structure that gives them greater consistency and durability.

Main application: Filling the tear trough and replacing lost volume.
Duration: About 9 to 12 months (depending on the brand and body physiology).
Advantages: Rapid correction of the hollow, predictable result, possibility of reversal with hyaluronidase in case of complications.
Risks: Bruising, swelling, Tyndall effect (blueness of the skin in superficial injections), lymphedema, or, in rare cases, vascular complications.

What is Mesogel (Skinbooster) and what does it do?

Mesotherapy or Mesogel injection in Shiraz involves the injection of non-crosslinked hyaluronic acid or polynucleotide compounds (PN/PDRN). These compounds do not have much filling properties, but they provide deep hydration and stimulate skin regeneration.
Main application: Improving skin quality (brightening, increasing transparency, eliminating fine lines and thinning of the skin).
Duration: Results are seen after 2–3 sessions and usually require maintenance sessions every 6–12 months.
Benefits: Natural rejuvenation without significant volume change, improved skin texture and radiance.
Risks: Possible temporary inflammation, redness, or small nodules; but the vascular risk is lower than with fillers.

The main difference between fillers and mesogel under the eyes in Iran

Under-eye filler injections in Shiraz are primarily used to fill hollows and replace lost volume. In contrast, mesogels or skin boosters are utilized to enhance skin quality, hydrate the skin, and reduce fine lines. Simply put, fillers add volume, but mesogels rejuvenate and rejuvenate the skin. Let’s take a closer look at these:

Feature	Under-eye filler (HA cross-linked)	Mesogel / Skin Booster (Non-Crosslinked HA / PN)
Main purpose	Fillering hollows and volumizing	Improves skin quality, hydration, and clarity
Speed of result	Immediate (after injection)	Gradual (2–3 sessions)
Permanence	About 9–12 months	Requires 6–12 months of maintenance
Reversibility	Yes, with hyaluronidase	No
Suitable for	Deep hollows and hollows	Dull, thin or wrinkled skin

It should be noted that the term “under-eye bags” refers to the dark hollows and depressions under the lower eyelid that make the eyes look tired or older.

Choosing the right method for under-eye treatment in Iran

The choice between filler and mesotherapy (mesogel/skin booster) depends on the individual’s condition and the desired goal. Below, we review the most important criteria:

1. Presence of deep hollows or hollows

o If your main problem is true hollows and depressions under the eyes, hyaluronic acid filler is the best option. This method directly replaces the lost volume and corrects the tired appearance of the eyes.

2. Skin quality and consistency

o In people with thin, dry, dull skin or superficial fine lines, mesogel or skin boosters are a more logical choice, because they naturally improve the quality of the skin by hydrating and stimulating collagen.

3. Aesthetic expectations

If you are looking for a quick and visible change, fillers will respond better.
- If your goal is gradual and natural rejuvenation without a large volume change, Mesogel is more suitable.

4. Condition of fat bags and puffiness under the eyes

In people with excessive puffiness or lymphedema, filler injections can worsen the condition; in these cases, Mesogel or complementary treatments are recommended.

5. Age and gender

In younger people with healthy skin, Mesogel can be useful for preventing premature aging.
- At older ages, when fat loss and sagging are more pronounced, fillers will be a more effective option.

6. Personal preferences

If safety and the possibility of correction are a priority for you, HA fillers are superior due to their ability to be dissolved with hyaluronidase.
- If you desire rejuvenation without a sudden volume change, Mesogel is a more natural choice.

Miracle of Rejuvenation at Irsa clinic
Fotona laser in Iran

Risks and safety tips in under-eye treatment

The under-eye area is one of the most sensitive parts of the face, and any injection in this area requires high precision and the experience of a specialist doctor. Choosing the wrong method or injection by non-specialists can cause serious complications.

1. Risks of under-eye filler injection

Bruising and swelling: The most common complication, which usually resolves within 7 to 14 days.
Tyndall effect (blueness under the skin): occurs in the case of superficial injection or use of an inappropriate filler.
Malar edema (lymphatic swelling): especially in susceptible patients or when injecting large volumes.
Vascular complications (very rare but serious): Vascular occlusion can lead to tissue damage or even vision problems.
Abnormal results: if the wrong technique is chosen or excessive injection is made.

2. Risks of Mesogel and Skin Boosters

Temporary redness and swelling: usually disappears within a few days.
Nodules or small bumps: If injected incorrectly or sterile protocols are not followed.
Infection: Although unlikely, it does exist.
Less than expected results: Since Mesogel improves the quality of the skin more, it may not be enough for people with deep hollows.

3. Essential safety tips

Choosing a doctor experienced in under-eye anatomy, such as Dr. Mostafa Emadi as one of the best filler injection doctors in Shiraz, is the most important factor in preventing complications.
Using reputable, FDA or CE-certified products.
Avoiding injections in unauthorized clinics or by people without medical qualifications.
Starting treatment with a small volume and a gradual approach to achieve a natural and safe result.
In the case of HA fillers, ensure that the doctor has access to hyaluronidase for emergencies.

Safety summary:

Fillers = higher risk but immediate and correctable results.
Mesogel = less risk and gradual, but not enough for deep hollowing.
In both methods, choosing a specialist doctor and a reputable clinic is the key to having a natural and safe result.

The best brand of under-eye filler; which ones are safer and more effective?

Among the types of gels available for under-eye injection, several brands are both known for their safety and their results have been confirmed in clinical studies. Here are a few examples:

Brand	Highlights
Juvéderm Volbella XC	The first and only filler to be officially approved by the FDA for tear trough correction; a soft gel with a viscosity suitable for the sensitive under-eye area. AbbVie News Center+2The Zoe Report+2
Restylane Eyelight	A product from Galderma designed to brighten the appearance of under-eye circles and treat hollows; it was also recently approved by the FDA. Harmon Facial Plastic Surgery+2eleglobals.com+2
Teosyal Redensity II	A combination of hyaluronic acid and nutrients such as amino acids to improve skin quality, reduce dark circles and under-eye bags; known as an option with fewer side effects than thicker fillers. Ai Beauty Clinic+2Feau+2

Please note that:

The skill of the doctor and the injection technique are more important than the brand itself. Even the best brand may not give the desired results or cause complications if used by an unskilled doctor or with the wrong technique.
It is very important to ensure the authenticity of the brand, the authentic packaging and the correct expiration date.

The number of sessions for under-eye filler injections in Shiraz for different brands

The number of sessions for under-eye filler injections usually depends on the type of product and the individual’s condition, but for the main brands it can be categorized as follows:

Brand	Typical number of sessions	Additional explanation
Juvéderm Volbella XC	Usually 1 session is enough	Due to its good consistency and relatively long lasting effect (12–18 months), the desired result is often achieved with a single injection. In some people, a small touch-up session is required after 4–6 weeks.
Restylane Eyelight	1 main session + possibly 1 follow-up session	This product is designed to be natural. Usually, one injection is enough, but in cases of deep hollows, the doctor may recommend a small additional amount after 2–3 weeks. The duration is about 9–12 months.
Teosyal Redensity II	1–2 sessions	Because in addition to the filling, it also helps the quality of the skin, the doctor may perform the treatment in two stages (for example, 70% in the first session and 30% in the next session). Duration 9–12 months.

In most patients, one main session is sufficient, and finally a small touch-up session is performed after a few weeks. In under-eye injections, an experienced ophthalmologist or dermatologist and the best under-eye filler injection doctor in Shiraz usually prefers to do the work in stages and conservatively, rather than injecting a large volume at once, so that the result is more natural and safer.

Mesogel brands for under-eye injections in Shiraz
Iran

When choosing the right brand for under-eye mesogel injections, it is important to pay attention to quality, effective ingredients, and the doctor’s experience. Below, we will introduce some reputable mesogel brands for this area:

1. Jalupro:

A combination of hyaluronic acid and amino acids that helps regenerate and rejuvenate the skin. It is effective for removing dark circles and hollows under the eyes.

2. Profhilo:

With the highest concentration of hyaluronic acid, it helps to hydrate and lift the skin. Suitable for thin and sensitive skin under the eyes.

3. Belamin:

A combination of hyaluronic acid and nutrients that helps improve the quality and firmness of the skin. Recommended for sensitive areas such as under the eyes.

4. Proage:

A combination of hyaluronic acid and vitamins that helps regenerate and strengthen the skin. Effective for removing wrinkles under the eyes.

5. Rejuveyes:

A combination of hyaluronic acid and peptides that helps reduce puffiness and darkness under the eyes. Suitable for sensitive and thin skin.

Ultimately, choosing the right brand should be done in consultation with a specialist and according to the specific needs of your skin.

Number of sessions required for the injection of different types of mesogels

For each of the leading brands of mesogel under the eyes, the typical number of sessions is as follows (these values are approximate and may vary depending on skin condition, age, severity of the problem, and doctor’s opinion):

1. Jalupro

Usually 2-3 sessions are recommended at 3-4 week intervals.
After the initial period, maintenance sessions may be required every 6-12 months.

2. Profhilo

Two sessions of Profhilo are usually sufficient at 4 week intervals.
Its effects last for 6-8 months, and maintenance sessions can be performed every 6 months.

3. Belamin

Typically 2-3 sessions are performed at 3-4 week intervals.
Maintenance sessions are recommended every 6-12 months.

4. Proage

2-3 initial sessions at 3-4 week intervals are required to achieve the desired results.
Then, to maintain the effects, annual sessions or every 6–12 months are recommended.

5. Rejuveyes

Usually 2–3 sessions at 3–4 week intervals are sufficient.
Maintenance of results can be achieved with one session every 6–12 months.

Note: The severity of skin darkening or dryness, age, skin quality, and previous care history will affect the final number of sessions. It is always recommended to have the exact schedule of sessions determined by a specialist.

Below is a comprehensive comparison table of mesogel brands suitable for the under-eye area, including the recommended number of sessions, therapeutic effects, benefits, and key points of each brand:

Mesogel Brand	Suggested number of sessions	Interval between sessions	Main therapeutic effects	Key Benefits & Tips
Jalupro	2–3 sessions	2–4 weeks	Deep hydration, improving skin quality, reducing dark circles and fine lines	Suitable for thin and sensitive skin under the eyes, requires precise injection technique, can be used on face and neck Jalupro2
Profhilo	2 sessions	4 weeks	Increase skin moisture and elasticity, improving overall skin quality
Belamin	2–3 sessions	3–4 weeks	Improvement of skin tone and texture, reducing dark circles and puffiness under the eyes	BAP technique for injection, suitable for aging and loose skin, requires maintenance every 6–9 months SIAN Skin Clinic
Proage	6–10 sessions	7–15 days or monthly	Boost collagen, improving skin elasticity and firmness
Rejuveyes	6 initial sessions + 4 maintenance sessions	3 months for the initial period, then every 6–12 months	Reducing puffiness, dark circles and wrinkles around the eyes, hydrating and firming the skin	Suitable for dull and tired skin, requires precise injection technique, long-lasting effects Renew MedSpa

Important note: The number of sessions and the interval between them may vary depending on the individual’s skin condition, the severity of the existing problems, and the opinion of the specialist. Also, to achieve the best results, choosing the right brand and the correct injection technique is very important.

Care before injecting fillers under the eyes in Shiraz

Care before injecting fillers under the eyes includes:

1. Discontinuation of blood thinners (in consultation with a doctor)

5–7 days before, if medically possible, aspirin, ibuprofen and other NSAIDs, vitamin E, omega-3 and anticoagulants should be stopped.

2. Avoid alcohol and tobacco:

Alcohol and cigarettes can increase bruising and swelling.

3. Get enough sleep and rest:

Lack of sleep and stress can cause more swelling.

4. No makeup on the day of injection:

Clean skin helps reduce the risk of infection.

5. Inform your doctor completely:

About diseases (such as clotting problems, allergies or skin diseases) and medications you are taking.

Aftercare for under-eye filler injections

Aftercare for under-eye filler injections includes:

1. Intermittent cold compresses:

In the first 24-48 hours, a cold compress for 10 minutes every few hours helps reduce bruising and swelling.

2. Sleeping with your head elevated:

For the first 2-3 nights, sleep with two pillows so that less fluid accumulates around the eyes.

3. No pressure or massage on the injection area:

The area should not be manipulated or massaged for 10-14 days unless advised by a doctor.

4. Avoiding strenuous activity:

Heavy exercise, saunas and jacuzzis are prohibited for at least 3 days.

5. Avoiding heavy cosmetics:

It is better not to wear any makeup on the skin for the first 24 hours.

6. Follow-up treatment (if needed):

A follow-up appointment is usually scheduled after 2–4 weeks to make minor adjustments if needed.

Warning signs:

If you experience pain, vision changes, unusual white spots or patches on the skin, or progressive swelling after the injection, you should see a doctor immediately. (These are rare but require immediate action.)

Frequently Asked Questions from Users

1. Which is longer-lasting: fillers or mesogel?

Fillers usually last longer (9–12 months).
Mesogel requires multiple sessions and maintenance, but it naturally improves skin quality.

2. Can mesogel replace fillers?

No. Mesogel is not designed to fill deep hollows. If you have obvious hollows, fillers are the first choice.

3. Are under-eye fillers dangerous?

It is safe when performed by a skilled practitioner who is familiar with the anatomy. The risks are mostly related to poor technique, and fortunately, they can be corrected with HA fillers.

4. Who is Mesogel not suitable for?

Mesogel is not a good choice for people with excessive puffiness, lymphedema, or active skin conditions.

5. Which costs more?

• Filler injections usually cost more per session.

• Mesogel requires repeated sessions, and over time, the total cost may be close to fillers.

Conclusion

The choice between Mesogel and under-eye fillers depends on your main problem. Fillers are a quick and effective option for filling hollows and restoring lost volume, while mesotherapy or Mesogel focuses more on improving the quality, hydration, and rejuvenation of the skin. Many experts believe that a gradual combination of the two methods is the best way to create a natural, safe, and lasting result.

If you have hollows or halos under your eyes and need quick results; fillers are the best choice.
If your problem is more about dull skin, fine lines, or thin skin, and you are also looking for gradual rejuvenation, Mesogel or Skin Boosters are more effective.
In many cases, a gradual combination of these two methods gives the best results.

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